The calcitonin gene-related peptide family - form, function and future perspectives

PThis book contains a comprehensive series of reviews on the calcitonin gene-related peptide (CGRP) family of peptides. This family of peptide hormones has a diverse and constantly expanding range of important physiologic functions, including regulation of blood calcium, vascular tension, feeding behavior and pain recognition. /P P/P PThis volume includes chapters on: /P UL P LIThe adrenomedullin peptides and signalling/LI P/P P LILigand binding and activation of the CGRP receptor /LI P/P P LIUnderstanding amylin receptors /LI P/P P LIThe CGRP-receptor component protein/LI P/P P LIThe calcitonin peptide family/LI P/P P LIGenetic regulation of CGRP/LI P/P P LIVascular actions of CGRP and adrenomedullin /LI P/P P LIIntermedin/adrenomedullin 2 function/LI P/P P LICGRP and adrenomedullin as pain-related peptides/LI P/P P LIAmylinergic control of ingestive behaviour/LI P/P P LICalcitonin receptors/LI P/P/UL P/P PThis book discusses their receptors, physiological and pathophysiological functions and potential as clinical targets.
It will appeal to researchers who study any of these peptides and those with an interest in migraine therapy due to the involvement of CGRP in this disorder. The book is unique because it brings together research on the whole peptide family for the first time in several years. It will be a useful reference volume for researchers in this area. This book will also appeal to researchers in the broader field of bioactive peptides./P