Une pure merveille !
Un roman d'une grande beauté, drôle, fin, extrêmement lumineux sur des sujets difficiles : la perte de
l'être aimé, la dureté de la vie et la tristesse qu'on barricade parfois... Elise franco-japonaise,
orpheline de sa maman veut poser LA question à son père et elle en trouvera le courage au fil des pages,
grâce au retour de sa grand-mère du japon, de sa rencontre avec son extravagante amie Stella..
Ensemble il ne diront plus Sayonara mais Mata Ne !
This series of short texts provides accessible accounts of a range of essential topics in chemistry and chemical engineering. Written with the needs of...
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Livré chez vous entre le 27 septembre et le 3 octobre
En librairie
Résumé
This series of short texts provides accessible accounts of a range of essential topics in chemistry and chemical engineering. Written with the needs of the student in mind, the " Oxford Chemistry Primers " offer just the right level of detail for undergraduate study, and will be invaluable as a source of material commonly presented in lecture courses yet-not adequately covered in existing texts. All the basic principles and facts in a particular area are presented in a clear and straightforward style, to produce concise yet comprehensive accounts of topics covered in both core and specialist courses. Many of today's best selling drugs are first made in the chemical laboratory on a very small scale many years before they enter the market place. During the intervening period, organic chemists investigate alternative methods both to improve the overall yield of the process and to ensure that it operates safely on a manufacturing scale. "Top Drugs : Top Synthetic Routes" reviews the syntheses of the best selling drugs used in tackling many of the major categories of human disease cardiovascular, gastrointestinal, central nervous system, inflammatory and infectious diseases-comparing the original research method used in the discovery programme with more recent approaches aimed Ether at improving the development route or at validating newer methodologies or reagents in the context of drug synthesis. This Primer clearly explains how an understanding of modern organic chemistry is pivotal to the overall drug discovery process and will allow students to see how the organic chemistry taught in undergraduate courses is applied by medicinal chemists in industry.
Sommaire
Inhibitors of angiotensin converting enzyme as effective antihypertensive agents
Blockade of angiotensin-H receptors
Calcium channel blockers in the treatment of angina and hypertension
Antagonists of histamine receptors (H2) as anti-ulcer remedies
Proton pump inhibitors as gastric acid secretion inhibitors
Modulation of central serotonin in the treatment of depression
Hypnotic, anxiolytic, anticonvulsant and muscle relaxant agents : ligands for benzodiazepine receptors
Another histamine receptor : blockers of the Hl receptor for the treatment of seasonal allergic rhinitis
Nucleoside analogues which inhibit HIV reverse transcriptase
Quinolones as anti-bacterial DNA gyrase inhibitors.