Une pure merveille !
Un roman d'une grande beauté, drôle, fin, extrêmement lumineux sur des sujets difficiles : la perte de
l'être aimé, la dureté de la vie et la tristesse qu'on barricade parfois... Elise franco-japonaise,
orpheline de sa maman veut poser LA question à son père et elle en trouvera le courage au fil des pages,
grâce au retour de sa grand-mère du japon, de sa rencontre avec son extravagante amie Stella..
Ensemble il ne diront plus Sayonara mais Mata Ne !
The topics presented here include mechanism of action of anti-inflammatory drugs, enzymes involved in arachidonic acid metabolism, their cloning and crystal...
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Livré chez vous entre le 2 octobre et le 8 octobre
En librairie
Résumé
The topics presented here include mechanism of action of anti-inflammatory drugs, enzymes involved in arachidonic acid metabolism, their cloning and crystal structure, the effect of inhibitors and cell knockout, novel receptors and their mechanism of signal transduction, anti-inflammatory eicosanoids and eicosanoid regulation of inflammation and metastasis. Understanding the cellular and molecular basis of the inflammatory response continues to evolve with the discovery of new pathways and mediators. The quest for new anti-inflammatory agents depends on the elucidation of biochemical pathways involved in the initiation and termination of the inflammatory response. The topics presented here are state of the art and provide insights into novel approaches.
Sommaire
The Mechanism of Action of anti-inflammatory Drugs
Human Group-V Phospholipase-A² Expression in Pichia pastoris and Its Role in Eicosanoid Generation
Fatty-Acid Substrate Interactions with Cyclooxygenases
Structure, Function and Inhibition of Cyclooxygenases
Leukotriene-A4 Hydrolase: Probing the Active Sites and Catalytic Mechanisms by Site-Directed Mutagenesis
The Regulation of Cyclooxygenase-1 and -2 in Knockout Cells and Cyclooxygenase and Fever in Knockout Mice
Leudotriene-B4 Receptor and Signal Transduction
Lipoxins, Aspirin-Triggered 15-epi-Lipoxin Stable Analogs and Their Receptors in Anti-inflammation: a Window for Therapeutic Opportunity
Lipoxin-Stable Analogs: Potential Therapeutic Downregulators of Intestinal Inflammation
The Role of Eicosanoids in Tumor Growth and Metastasis.