The Human Memory

This book is a Weekend Pocketbook on Everything You Should Know About the Encoding of Life, the hidden information systems that allow the human body to remember, adapt, defend, and rebuild itself. Written in everyday language, we explore how life stores information not just in the brain, but across genes, cells, tissues, immunity, microbes, and even movement. How does the body remember who you are? We begin with the idea of information itself, from Claude Shannon's bit to Erwin Schrödinger's vision of genes as stable biological instructions.
We talk about how the body's deepest archive: deoxyribonucleic acid (DNA), the dense, durable molecule that stores inherited instructions in a four-letter code and has even inspired scientists to build DNA-based digital storage systems. We explore the body's rewriteable layers. Epigenetic marks act like annotations on the genetic script, changing how genes are read without changing the code itself.
Prions show another strange form of biological memory, in which proteins pass information through their shape. These systems imply that biology does not simply store information once; it edits, highlights, silences, and updates it as life unfolds. We follow the fast memory systems that make experience possible. We discuss neurons, synapses, action potentials, long-term potentiation, memory traces, sleep replay, connectomics, and the brain's astonishing ability to store and retrieve information while running on about the power of a small light bulb. We also explore immune memory, in which B cells, T cells, antibodies, vaccines, and long-lived plasma cells maintain a distributed record of threats the body has faced before.
We end at the frontier, where scientists are learning to write information into DNA, engineer living recorders, build brain-computer interfaces, and grow brain organoids. If life is memory in motion, how far should we go in rewriting the story our bodies carry?