This second edition has been extensively revised, updated, and enlarged to include new material covering the most recent topics and applications in this fast-moving field. The book contains stateof-the-art protocols and applications on all aspects of Peptide Nucleic Acids (PNA) and in addition describes the theory and history of PNA. Concepts are explained clearly and in practical terms and each chapter contains concise background information. Written by leading experts in the field, the book is an invaluable contribution to this novel and exciting area. An important reference text and laboratory manual for all molecular biologists.