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Sjogren’s Syndrome, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions
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- FormatePub
- ISBN978-1-370-03499-4
- EAN9781370034994
- Date de parution20/09/2016
- Protection num.pas de protection
- Infos supplémentairesepub
- ÉditeurEditeurs divers USA
Résumé
Sjogren's syndrome is a medical disorder that most frequently produces dry eyes and mouth. It is a form of autoimmune disease. It can be Primary and Secondary if it occurs with other autoimmune diseases:1. Rheumatoid arthritis2. Systemic lupus erythematosus.3. SclerodermaThere is lymphocytic invasion of exocrine glands, inducing the main symptoms of:1. Xerophthalmia (dry eyes), 2. Xerostomia (dry mouth) and3.
Enlargement of the parotid glandsThe causes are1. Genetic:There is a genetic predisposition for the disorder but the HLA link changes among ethnic groups.2. Development of complications such as neuropathy and lymphoma may tend to be common in patients with vitamin D deficiency. Nine out of ten people who have the disorder are women. People normally first begin noticing symptoms when they are in their 30s or 40s.
Symptoms are:1. Dry mouth2. Dry Eyes3. Dry mouthOther symptoms may be:1. Fatigue2. Fever3. Change in the color of hands or feet4. Joint pain or joint swelling5. Swollen glandsAutoimmune screening tests may then show a positive rheumatoid factor and antinuclear antibodiesDryness of the mucosa of the trachea and bronchi may manifest as a dry coughThe dryness of the pharynx and esophagus may cause difficulty in swallowing, and lack of saliva and secretions may predispose to gastro-esophageal refluxThere can be dry skin and vaginal dryness causing dyspareuniaDisease of the pancreas can lead to malabsorption and even acute pancreatitis or chronic pancreatitis but a frequent cause of raised serum amylase is parotitis.
Fatigue is a common featureAbout 20% have Raynaud's phenomenon. The treatment is to relieve the symptoms as there is no cure.1. Dry eyes may be treated with artificial tears, eye-lubricating ointments, or cyclosporine eye drop2. Other medicines may be:a. Steroids: these are tablets taken by mouth that assist to decrease inflammation. They may be given if the symptoms are particularly bad.b. Immunosuppressive agents: these are medicines that suppress the abnormal antibody production in Sjogren's syndromeMedicines are methotrexate, penicillamine and hydroxychloroquine.
Sjogren's syndrome is not normally life-threatening. TABLE OF CONTENTIntroductionChapter 1 Sjogren's SyndromeChapter 2 CausesChapter 3 SymptomsChapter 4 DiagnosisChapter 5 TreatmentChapter 6 PrognosisChapter 7 Rheumatoid ArthritisChapter 8 Dry EyesEpilogue
Enlargement of the parotid glandsThe causes are1. Genetic:There is a genetic predisposition for the disorder but the HLA link changes among ethnic groups.2. Development of complications such as neuropathy and lymphoma may tend to be common in patients with vitamin D deficiency. Nine out of ten people who have the disorder are women. People normally first begin noticing symptoms when they are in their 30s or 40s.
Symptoms are:1. Dry mouth2. Dry Eyes3. Dry mouthOther symptoms may be:1. Fatigue2. Fever3. Change in the color of hands or feet4. Joint pain or joint swelling5. Swollen glandsAutoimmune screening tests may then show a positive rheumatoid factor and antinuclear antibodiesDryness of the mucosa of the trachea and bronchi may manifest as a dry coughThe dryness of the pharynx and esophagus may cause difficulty in swallowing, and lack of saliva and secretions may predispose to gastro-esophageal refluxThere can be dry skin and vaginal dryness causing dyspareuniaDisease of the pancreas can lead to malabsorption and even acute pancreatitis or chronic pancreatitis but a frequent cause of raised serum amylase is parotitis.
Fatigue is a common featureAbout 20% have Raynaud's phenomenon. The treatment is to relieve the symptoms as there is no cure.1. Dry eyes may be treated with artificial tears, eye-lubricating ointments, or cyclosporine eye drop2. Other medicines may be:a. Steroids: these are tablets taken by mouth that assist to decrease inflammation. They may be given if the symptoms are particularly bad.b. Immunosuppressive agents: these are medicines that suppress the abnormal antibody production in Sjogren's syndromeMedicines are methotrexate, penicillamine and hydroxychloroquine.
Sjogren's syndrome is not normally life-threatening. TABLE OF CONTENTIntroductionChapter 1 Sjogren's SyndromeChapter 2 CausesChapter 3 SymptomsChapter 4 DiagnosisChapter 5 TreatmentChapter 6 PrognosisChapter 7 Rheumatoid ArthritisChapter 8 Dry EyesEpilogue























