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Leukocytosis, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions

Par : Kenneth Kee
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  • FormatePub
  • ISBN978-1-370-38110-4
  • EAN9781370381104
  • Date de parution18/11/2016
  • Protection num.pas de protection
  • Infos supplémentairesepub
  • ÉditeurEditeurs divers USA

Résumé

Leukocytosis is a medical disorder when the white blood cell count (the leukocyte count) is higher than the normal range in the bloodHigh white blood cell count is a higher amount in disease-fighting cells (leukocytes) circulating in the blood. Leukocytosis is frequently a sign of the inflammatory response most commonly due to infection, but may also happen after certain parasitic infections or bone tumors.
It may also happen after convulsions such as epilepsy, emotional stress, strenuous exercise, pregnancy and labor, anesthesia, and epinephrine injection. A high white blood cell count normally suggests a:1. Raised production of white blood cells to fight an infection2. Reaction to a drug that increases white blood cell production3. Disorder of bone marrow, resulting in abnormally high production of white blood cells4.
Immune system disorder that produces higher white blood cell productionThere are five principal types of leukocytosis:1. Neutrophilia (the most common form)2. Lymphocytosis3. Monocytosis4. Eosinophilia5. BasophiliaThe mechanism that produces leukocytosis can be of several forms:1. A higher release of leukocytes from bone marrow storage pools, 2. Decreased margination of leukocytes onto vessel walls, 3.
Decreased extravasation of leukocytes from the vessels into tissues, 4. An increase in amount of precursor cells in the marrowCertain medicines may cause leukocytosis including:1. Corticosteroids, 2. Lithium3. Beta agonistsA high white blood cell count of more than 11, 000 leukocytes in a micro-liter of blood in adults is normally considered leukocytosis. The high end for a high white blood cell count in children depends on the child's age and sizeLeukapheresis or exchange blood transfusion is a treatment of choice for this purpose with:1.
Hydration, 2. Urine alkalinization, 3. Administration of rasburicase (uric acid oxydase) or allopurinol to decrease blood uric acid and minimize tumor lysis syndrome. When rasburicase is used, urine alkalinization is not recommended. Definitive treatment of underlying cause is promptly instituted with appropriate chemotherapyTABLE OF CONTENTIntroductionChapter 1 LeukocytosisChapter 2 CausesChapter 3 SymptomsChapter 4 DiagnosisChapter 5 TreatmentChapter 6 PrognosisChapter 7 EosinophiliaChapter 8 LeukemiaEpilogue