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Diabetes Mellitus Type 3c, (Pancreatogenic Diabetes) A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions

Par : Kenneth Kee
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  • FormatePub
  • ISBN978-1-370-50820-4
  • EAN9781370508204
  • Date de parution03/12/2017
  • Protection num.pas de protection
  • Infos supplémentairesepub
  • ÉditeurEditeurs divers USA

Résumé

This book describes Pancreatogenic Diabetes, Diagnosis and Treatment and Related DiseasesJust a week ago I was emailed an article on Pancreatogenic DiabetesIntrigued I decided to look further into research papers and found that it is not as rare as it appeared. Pancreatogenic diabetes is a form of secondary diabetes that occurs when pancreatic inflammation, neoplasia, or resection leads to beta-cell dysfunction, affecting the secretion of insulin causing Types 3c Diabetes.
Type 3c diabetes is almost twice as frequent as type 1 diabetes but is misdiagnosed as type 2 diabetes in over 87% of patients. Type 3c diabetes patients tended about 1.5 times more likely to have poor glycemic control than those with type 2 diabetes and tended almost 10 times more likely to use insulin. Those with type 3c diabetes need insulin therapy more urgently than those with type 2, so the result of this misdiagnosis are delays in giving proper treatment leading to nerve, eye, and kidney damage.
Causes:1. Chronic pancreatitis is the most frequent disease of the exocrine pancreas linked with the development of diabetes2. Cystic fibrosis-related diabetes (CFRD)3. Lacking genes in the E2F group4. Finally, other less frequent forms of pancreatogenic diabetes are present, such as that due to pancreatic cancer, and post-pancreatectomy diabetesSymptoms:These symptoms are typical of diabetes:1. Frequent thirst even after drinking lots of water2.
Passing more frequent urine during day and night3. Weight lossMost patients with T3cDM have a known history of:1. Pancreatitis with abdominal pain, 2. Steatorrhea or3. Mal-digestion4. Nutritional deficiencies and5. Glucose intolerance. Patients may also manifest with symptoms of:1. Mal-digestion and2. Abdominal painDiagnosis:The diagnosis of T3cDM requires1. The evidence of pancreatic exocrine insufficiency (based on monoclonal fecal elastase 1 test)2.
Evidence of pathological pancreatic imaging (by endoscopic ultrasound, MRI)3. The absence of type 1 diabetes mellitus (T1DM)-linked auto-antibodiesConfirmation of T3cDM can then be made by report of an absent pancreatic polypeptide response to mixed-nutrient ingestionTreatment:The treatment of hyperglycemia to reach and maintain the HbA1c