Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters - Grand Format

Knowledge of cardiac ion channels and transporters has advanced remarkably in the last two decades with the development of patch-clamp and molecular biological techniques. This textbook offers a comprehensive overview of structures and functions of ion channels and transporters in the heart. Readers are first introduced to the molecular biology and electro-physiology of all the important ion channels.
After discussing their developmental changes, the pharmacology and pathophysiology of clinically-relevant ion channels are reviewed. Molecular aspects of the cardiac excitation-contraction coupling and intracellular Cal' regulation by ion transporters are also described. The book will be useful to electro-physiologists, cardiac physiologists and pharmacologists, and molecular biologists interested in ion channels at all levels.
For research specialists, the book will provide a perspective of the field. The book can be used as a reference source for working scientists in the fields of ion channels, biophysics, cardiac electrophysiology, and pharmacology. It is aimed at graduate and medical students, designed for use as a textbook for graduate and medical courses.