Interpretation of MS-MS Mass Spectra of Drugs and Pesticides
Par : ,Formats :
- Nombre de pages393
- PrésentationRelié
- FormatGrand Format
- Poids1.202 kg
- Dimensions21,8 cm × 28,2 cm × 2,8 cm
- ISBN978-1-118-50018-7
- EAN9781118500187
- Date de parution30/01/2017
- CollectionSeries on Mass Spectrometry
- ÉditeurWiley
Résumé
Mass spectrometry (MS) is an indispensable tool in structure elucidation and quantitative analysis of a wide variety of compound classes, such as drugs and pesticides. For this purpose, MS is mostly used in combination with either gas or liquid chromatography (GC-MS or LC-MS). In compound identification by LC-…
Mass spectrometry (MS) is an indispensable tool in structure elucidation and quantitative analysis of a wide variety of compound classes, such as drugs and pesticides. For this purpose, MS is mostly used in combination with either gas or liquid chromatography (GC-MS or LC-MS). In compound identification by LC-MS, extensive knowledge is needed on the fragmentation of even-electron ions in tandem mass spectrometry (MS-MS).
Interpretation of MS-MS Mass Spectra of Drugs and Pesticides details all of the relevant information on the fragmentation of drugs and pesticides, while proposing general fragmentation rules. Information about the fragmentation of drugs and pesticides in the scientific literature is both very scattered and rather incomplete. This book provides comprehensive information on fragmentation pathways of the various chemical compound classes.
Whenever available or useful, fragmentation in both positive-ion and negative-ion modes is discussed and compared. Interpretation of MS-MS spectra of important classes of compounds including drugs for cardiovascular diseases and hypertension, psychotropic or psychoactive compounds, drugs related to the gastrointestinal tract, antimicrobial compounds, and other classes of drugs, such as steroids, drugs of abuse, as well as pesticides and herbicides ; A general discussion on the fragmentation of even-electron ions in both positive-ion and negative-ion modes ; Important information on how to interpret spectra so that fragments that are not contained in a particular database can be correctly identified ; Discussion on interpretation strategies in different application areas of small-molecule LC-MS ; Introduction to MS-MS technology, concepts, and terminology used in mass spectral analysis ; As there is no comprehensive book on the interpretation of MS-MS mass spectra of small organic molecules, this book would of great interest to many scientists looking to interpret mass spectra of such compounds.
Interpretation of MS-MS Mass Spectra of Drugs and Pesticides details all of the relevant information on the fragmentation of drugs and pesticides, while proposing general fragmentation rules. Information about the fragmentation of drugs and pesticides in the scientific literature is both very scattered and rather incomplete. This book provides comprehensive information on fragmentation pathways of the various chemical compound classes.
Whenever available or useful, fragmentation in both positive-ion and negative-ion modes is discussed and compared. Interpretation of MS-MS spectra of important classes of compounds including drugs for cardiovascular diseases and hypertension, psychotropic or psychoactive compounds, drugs related to the gastrointestinal tract, antimicrobial compounds, and other classes of drugs, such as steroids, drugs of abuse, as well as pesticides and herbicides ; A general discussion on the fragmentation of even-electron ions in both positive-ion and negative-ion modes ; Important information on how to interpret spectra so that fragments that are not contained in a particular database can be correctly identified ; Discussion on interpretation strategies in different application areas of small-molecule LC-MS ; Introduction to MS-MS technology, concepts, and terminology used in mass spectral analysis ; As there is no comprehensive book on the interpretation of MS-MS mass spectra of small organic molecules, this book would of great interest to many scientists looking to interpret mass spectra of such compounds.