Sabine Chierici est enseignant-chercheur au département de chimie moléculaire de l'université Grenoble Alpes.
Exercise Book on Aromatic Nitrogen Heterocycles Chemistry. How to deal with the synthesis and reactivity of five- and six-membered rings
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- Nombre de pages230
- PrésentationBroché
- FormatGrand Format
- Poids0.418 kg
- Dimensions16,0 cm × 23,9 cm × 1,5 cm
- ISBN978-2-7598-3081-7
- EAN9782759830817
- Date de parution09/03/2023
- CollectionCurrent Natural Sciences
- ÉditeurEDP Sciences
Résumé
The book is organized in five sections. In the first chapter, typical syntheses along with metal catalyzed pathways are presented. The two following chapters are devoted to the chemical reactivity of the six-membered (pyridine, quinoline, azines) and five-membered rings (pyrrole, indole, azoles). In these two chapters, the exercises of increasing difficulties focus on the main types of reactions, including electrophilic and nucleophilic aromatic substitutions, N-alkylation and N-arylation, lithiation and other organometallic reactions, and metal catalyzed cross-coupling reactions.
In the fourth chapter, the principles discussed in the previous chapters will be applied to the chemistry of complex polycyclic heterocycles containing both five and six membered rings (pyrrolyl-pyridine, aza-indole, indolizine, purine). The exercises'solutions are commented in a separate chapter at the end of the book. Basic notions of nomenclature are given in a short appendix, allowing students to find out a ring structure from its name.
In the fourth chapter, the principles discussed in the previous chapters will be applied to the chemistry of complex polycyclic heterocycles containing both five and six membered rings (pyrrolyl-pyridine, aza-indole, indolizine, purine). The exercises'solutions are commented in a separate chapter at the end of the book. Basic notions of nomenclature are given in a short appendix, allowing students to find out a ring structure from its name.
The book is organized in five sections. In the first chapter, typical syntheses along with metal catalyzed pathways are presented. The two following chapters are devoted to the chemical reactivity of the six-membered (pyridine, quinoline, azines) and five-membered rings (pyrrole, indole, azoles). In these two chapters, the exercises of increasing difficulties focus on the main types of reactions, including electrophilic and nucleophilic aromatic substitutions, N-alkylation and N-arylation, lithiation and other organometallic reactions, and metal catalyzed cross-coupling reactions.
In the fourth chapter, the principles discussed in the previous chapters will be applied to the chemistry of complex polycyclic heterocycles containing both five and six membered rings (pyrrolyl-pyridine, aza-indole, indolizine, purine). The exercises'solutions are commented in a separate chapter at the end of the book. Basic notions of nomenclature are given in a short appendix, allowing students to find out a ring structure from its name.
In the fourth chapter, the principles discussed in the previous chapters will be applied to the chemistry of complex polycyclic heterocycles containing both five and six membered rings (pyrrolyl-pyridine, aza-indole, indolizine, purine). The exercises'solutions are commented in a separate chapter at the end of the book. Basic notions of nomenclature are given in a short appendix, allowing students to find out a ring structure from its name.
