Ebola and Marburg Viruses - Molecular and Cellular Biology

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Hans-Dieter Klenk et Heinz Feldmann - Ebola and Marburg Viruses - Molecular and Cellular Biology.
Ebola and Marburg viruses cause severe hemorrhagic fevers. Much research has been performed in recent years on the molecular and genetic properties of... Lire la suite
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Résumé

Ebola and Marburg viruses cause severe hemorrhagic fevers. Much research has been performed in recent years on the molecular and genetic properties of these viruses and in particular has focused on molecular structure, replication and virus-host interactions. This book presents a comprehensive review of the current research on these highly virulent viruses. Topics covered include the genomics and molecular biology of filoviruses, pathogenesis, replication, epidemiology, pathogenicity, approaches to vaccine development, virus-host interactions and the immune response.

Sommaire

    • Genome Organization, Replication and Transcription of Filoviruses
    • Structure of Viral Proteins
    • Structural and Functional Polymorphism of the Glycoproteins of Filovirusers
    • Molecular Mechanisms of Filovirus Entry
    • Roles of Filoviral Matrix-and Glycoproteins in the Viral Life Cycle
    • Virus Maturation
    • Filovirus Pathogenesis in Nonhuman Primates
    • Ebola Virus Infection in the Guinea Pig
    • Pathogenesis of Filovirus Infection in Mice
    • The Role of Endothelial Cells in Filovirus Hemorrhagic Fever
    • Modulation of Innate Immunity by Filoviruses
    • Cellular and Molecular Mechanisms of Ebola Pathogenicity and Approaches to Vaccine Development.

Caractéristiques

  • Date de parution
    01/01/2004
  • Editeur
  • ISBN
    0-9545232-3-7
  • EAN
    9780954523237
  • Présentation
    Relié
  • Nb. de pages
    318 pages
  • Poids
    0.885 Kg
  • Dimensions
    16,5 cm × 24,0 cm × 2,4 cm

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