Oncology: From Empiricism to Integrative Biology. Inaugural Lecture delivered on Thursday 8 January 2015
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- FormatMulti-format
- ISBN978-2-7226-0775-0
- EAN9782722607750
- Date de parution11/07/2024
- Protection num.NC
- Infos supplémentairesMulti-format incluant PDF avec W...
- ÉditeurCollège de France
Résumé
After decades of descriptive studies, the biology of cancer is undergoing a real revolution: with genetic approaches, researchers have identified many of the cell deregulations likely to drive tumours. A treatment combining arsenic and retinoic acid targets the protein responsible for promyelocytic leukaemia. This treatment, which has cured virtually all patients, gives hope that the in-depth understanding of carcinogenesis mechanisms may lead to new therapeutic approaches that could be transposed to other cancers.
After decades of descriptive studies, the biology of cancer is undergoing a real revolution: with genetic approaches, researchers have identified many of the cell deregulations likely to drive tumours. A treatment combining arsenic and retinoic acid targets the protein responsible for promyelocytic leukaemia. This treatment, which has cured virtually all patients, gives hope that the in-depth understanding of carcinogenesis mechanisms may lead to new therapeutic approaches that could be transposed to other cancers.