Dernière sortie
Solid-Phase Organic Synthesis
Efficient, high-throughput chemistry is now the focus of many research laboratories. Solid-phase organic syntheses are central to many of these combinatorial and parallel screening methodologies. Consequently, they have been a major scientific theme of the 1990s and promise to remain prominent for the first part of the new millennium. Indeed, a bewildering number of papers have entered the literature on this topic; some report minor modifications enabling, transformation of solution-phase methods to a solid support, while others report major innovations.
Solid-Phase Organic Synthesis collects, highlights, and critiques some of the key developments in the field. Leading practitioners explain different perspectives on diverse aspects of the area. Specific topics covered include:
• Syntheses of guanidines
• Palladium-catalyzed C-C bond forming reactions
• SnAr reactions for the formation of heterocycles
* Sequence-specific arylalkyne oligomers
* Resin-supported capture agents and other reagents
• Synthesis on pins
• Monitoring of supported reactions using IR
• Solid-phase syntheses of natural product derivatives
Efficient, high-throughput chemistry is now the focus of many research laboratories. Solid-phase organic syntheses are central to many of these combinatorial and parallel screening methodologies. Consequently, they have been a major scientific theme of the 1990s and promise to remain prominent for the first part of the new millennium. Indeed, a bewildering number of papers have entered the literature on this topic; some report minor modifications enabling, transformation of solution-phase methods to a solid support, while others report major innovations.
Solid-Phase Organic Synthesis collects, highlights, and critiques some of the key developments in the field. Leading practitioners explain different perspectives on diverse aspects of the area. Specific topics covered include:
• Syntheses of guanidines
• Palladium-catalyzed C-C bond forming reactions
• SnAr reactions for the formation of heterocycles
* Sequence-specific arylalkyne oligomers
* Resin-supported capture agents and other reagents
• Synthesis on pins
• Monitoring of supported reactions using IR
• Solid-phase syntheses of natural product derivatives
