There were two subjects which lonely widower Edward de Salis never discussed: his dead wife and his family home in Ireland, 'matchless Cashelmara'. So when he meets Marguerite, a bright young American with whom he can talk freely about both, he is able to love again and takes her back to Ireland as his wife. But Marguerite soon discovers that married life is not what she expected, and that she has married into a troubled family bitterly divided by love and hatred.
Cashelmara becomes the curse of three generations as they play out their fates in a spellbinding drama, which moves inexorably towards murder and retribution.