Chiral Separations by Chromatography focuses on developing or selecting suitable chromatographic methods for chiral separations. The book provides information on stereochemistry and separation and detection methods such as TLC, GLC, HPLC and CE; explores the importance of preparative separations-, and illustrates the importance or investigating the stereoisomeric composition of chemical compounds of biological significance. Also discussed are regulations and requirements as they apply to the development of pharmaceutical compounds. To further assist bench chemists in pharmaceutical fields, a detailed section is included on HPLC methods. A large number of examples are given that will assist in the selection of a method, including thin-layer chromatography, capillary electrophoresis and membrane separations.
This book will be a reliable guide for those just starting out in pharmaceutical and related industries, as well as those with experience in the field.