The Biological Chemistry Of The Elements. The Inorganic Chemistry Of Life, 2nd Edition

J-J-R Frausto Da Silva

,

R-J-P Williams

Note moyenne 
J-J-R Frausto Da Silva et R-J-P Williams - The Biological Chemistry Of The Elements. The Inorganic Chemistry Of Life, 2nd Edition.
Some twenty inorganic elements, many of them metals, are consistently found in living systems and are essential to the proper functioning of those systems.... Lire la suite
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Résumé

Some twenty inorganic elements, many of them metals, are consistently found in living systems and are essential to the proper functioning of those systems. The aim of this text is to discuss, describe, and explain the functional relevance of those the reasons for the processes of their uptake, transport, and localization in cells; the regulation of these processes; and the network of reactions that connects the in vivo inorganic elements to the environment and to the genome and the proteome. The first seven chapters describe the physical, chemical, and biological principles of the involvement of the elements in cellular activity. The next twelve chapters describe the uses of the individual inorganic elements: a section on the genetic control of each element is included. A final chapter explains how the interaction of genes, proteins, small molecules, and organic elements plays such an important role in evolution and speciation of organisms. The second edition of The biological chemistry of the elements is thoroughly revised in content and style. New to this edition are discussions of: the links to the genome of the uptake and transfer of elements and the regulation of homeostasis; the evolution of usage; the functional cooperative activities of the elements; interactions with the environment; and the influence of elements on evolution and speciation.

Sommaire

  • THE CHEMICAL AND PHYSICAL FACTORS CONTROLLING THE ELEMENTS OF LIFE
    • The chemical elements in biology
    • The principles of the uptake and chemical speciation of the elements in biology
    • Physical separations of elements: compartments and zones in biology
    • Kinetic considerations of chemical reactions, catalysis, and control
    • Energy in biological systems and hydrogen biochemistry
    • The role of biological macromolecules and polymers
    • The functional value of the chemical elements in biological systems
  • THE ROLES OF INDIVIDUAL ELEMENTS IN BIOLOGY
    • Sodium, potassium, and chlorine: osmotic control, electrolytic equilibria, and currents
    • The biological chemistry of magnesium: phosphate metabolism
    • Calcium: controls and triggers
    • Zinc: Lewis acid catalysis and regulation
    • Non-haem iron: redox reactions and controls
    • Haem iron: coupled redox reactions
    • Manganese: dioxygen evolution and glycosylation
    • Copper: extracytoplasmic oxidases and matrix formation
    • Nickel and cobalt: remnants of early life? Molybdenum, tungsten, vanadium, and chromium
    • Phosphate, silica, and chloride: acid-base non-metals
    • Sulphur, selenium, and halogens: redox non-metals
    • Integrated living systems of elements

Caractéristiques

  • Date de parution
    01/01/2001
  • Editeur
  • ISBN
    0-19-850848-4
  • EAN
    9780198508489
  • Présentation
    Broché
  • Nb. de pages
    575 pages
  • Poids
    1.35 Kg
  • Dimensions
    19,0 cm × 24,5 cm × 3,4 cm

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À propos des auteurs

J.J.R. Frausto da Silva is Professor of Analytical Chemistry, Instituto Superior Tecnico de Lisboa, Portugal. R. J. P. Williams is Emeritus Professor of Chemistry, University of Oxford.

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