Nuclear Receptors And Genetic Disease

Edward-R-B McCabe

,

Thomas-P Burris

Note moyenne 
Edward-R-B McCabe et Thomas-P Burris - Nuclear Receptors And Genetic Disease.
Nuclear Receptors and Genetic Disease offers a unique perspective, focusing on the molecular biology of nuclear receptor action and its relationship to... Lire la suite
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Résumé

Nuclear Receptors and Genetic Disease offers a unique perspective, focusing on the molecular biology of nuclear receptor action and its relationship to pathophysiology. Structured for ease of reference, each chapter provides information on the history, physiology, structure, mechanism of action, genetics, pathophysiology, disease diagnosis and pharmacology for a specific nuclear receptor. A comprehensive list of mutations for each receptor detailing localisation, biochemical phenotype and clinical phenotype is also included making this work an invaluable resource. Nuclear Receptors and Genetic Disease is essential reading for both basic and clinical scientists in the field of endocrinology, biochemistry, molecular biology, cell and developmental biology, and gene expression. It will also be of key interest to those working in pharmacology and reproductive biology, clinicians in endocrinology, clinical genetics, oncology, obstetrics and gynaecology.

Sommaire

    • The nuclear receptor superfamily
    • Thyroid hormone receptors
    • Estrogen and progesterone receptors
    • The androgen receptor
    • DAX-1 and related orphan receptors
    • The vitamin D receptor
    • Retinoid receptors
    • Mineralocorticoid and glucocorticoid receptors
    • Hepatocyte nuclear factor 4?
    • Peroxisome proliferator-activated receptors
    • Coactivators and corepressors.

Caractéristiques

  • Date de parution
    01/01/2001
  • Editeur
  • ISBN
    0-12-146160-2
  • EAN
    9780121461607
  • Présentation
    Relié
  • Nb. de pages
    419 pages
  • Poids
    0.865 Kg
  • Dimensions
    17,3 cm × 25,1 cm × 3,0 cm

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